Clinical Department Blueprints
Healthcare workflows vary significantly across departments. The following ten blueprints outline the clinical scenarios, step-by-step executions, technical implementations, privacy controls, and medical outcomes for scaling Agentic AI.
1. Radiology (PACS & Report Drafting)
Clinical Scenario: A clinician accesses the PACS viewer, triggering a SMART App Launch session. The interface (MCP Host) initializes an agent pod.
Execution:
- The agent calls upon Episodic Memory to parse historical diagnostic text notes.
- The agent automatically tracks subtle variations between the active scan and past baselines.
- The agent drafts a radiology report and submits it to the HITL clinician queue.
- The clinician validates and signs off on the report before final EHR commit.
Technical Implementation:
- Ingestion: Pulls raw DICOM metadata from cloud-agnostic object storage (Bronze).
- State Management: Transactional state stored in CockroachDB (Silver).
- Vector Retrieval: Vectorized historical reports matched in Milvus (Diamond).
- Orchestration: Agent Gateway routes the comparison and drafting workflow; the Tool Contract Registry (Platinum) versions the drafting tool’s schema.
Privacy & Memory Controls: Pre-LLM Pseudonymization hooks mask direct patient attributes. The agent uses fuzzy matches across Vector Stores to track structural changes over time.
Clinical Outcome: 34% reduction in critical finding turnaround times; zero missed incidental findings.
2. Clinical Lab & Pathology (Reflex Testing & Panic Alerting)
Clinical Scenario: Telemetry feeds from laboratory automation lines ingest raw lab results.
Execution:
- Lab results stream into the Bronze layer and sync to Silver’s write-side database.
- If a value crosses a panic threshold, a CDS Hook triggers an alert inside the EHR workspace.
- The alert launches an agent that retrieves clinical history.
- For routine boundaries, the agent executes reflex-testing tools autonomously.
- For critical panic values, the agent routes to a pathologist for HITL verification.
Technical Implementation:
- Ingest: Lab instrument streams landing in Bronze via Flink.
- State: Real-time relational tracking in CockroachDB (Silver).
- Orchestration: Tool contracts and reflex-testing routing rules enforced via the Platinum Tool Contract Registry and Agent Gateway.
Privacy & Memory Controls: Outbound payloads pass through a cluster-level Tokenization hook, swapping internal sample IDs with vault-backed tokens before external registry lookup.
Clinical Outcome: Sepsis identification window shortened by 4.2 hours; 19% reduction in unnecessary repeat draws.
3. Cardiology (ECG Waveform & Telemetry Alerting)
Clinical Scenario: High-frequency cardiac monitoring devices stream continuous physiological data.
Execution:
- Continuous ECG data streams ingest into Bronze.
- Flink aggregates and structures data into 1-minute intervals inside Silver.
- A cardiac agent evaluates metrics across active Working Memory.
- Normal patterns are summarized; abnormal rhythms trigger emergency escalation tools.
- The care team validates the alert to initiate immediate intervention.
Technical Implementation:
- Ingest: IoT streams in Bronze.
- State: Relational vitals database in Silver.
- Semantic: Feature store for predictive metrics in Diamond.
- Orchestration: Emergency protocols and logging handled in Platinum.
Privacy & Memory Controls: Post-LLM Masking hooks swap real waveform metrics with structurally identical placeholders for downstream analytics pipelines.
Clinical Outcome: Malignant arrhythmia detection improved by 28%; general floor code-blue incidents reduced by 41%.
4. Oncology (Genomic Profiling & Clinical Trial Matching)
Clinical Scenario: A patient is diagnosed with a specific cancer subclass, requiring treatment trial matching.
Execution:
- The oncology agent queries patient staging and genomic history.
- The agent queries Diamond for clinical trial guidelines and literature embeddings.
- The agent maps data profiles using SMART on FHIR specifications.
- The agent proposes a trial matching matrix to the Tumor Board.
- The multi-disciplinary Tumor Board conducts a HITL review to approve or modify recommendations.
Technical Implementation:
- Ingest: Genomic variant files and records in Bronze/Silver.
- Semantic: RAG guidelines index in Diamond (Milvus).
- Orchestration: Supervisor-Critic loops and treatment proposed ledgers in Platinum.
Privacy & Memory Controls: Genomic variant arrays pass through an Anonymization hook before matching against external registries. Agents traverse Temporal Graph Stores to resolve dependencies.
Clinical Outcome: Clinical trial enrollment increased by 55%; tumor board preparation times reduced from days to minutes.
5. Pharmacy (Drug-Drug Interaction Guardrails)
Clinical Scenario: A clinician enters a new medication order in the EHR.
Execution:
- A CDS Hook intercept routes the session context to the pharmacy agent.
- The agent accesses Silver for active prescriptions and Diamond for interaction graphs.
- The agent executes renal clearance calculations and scans for drug-drug interactions.
- If an interaction is found, the agent proposes a dose adjustment or alternative drug.
- A clinical pharmacist signs off on the dose adjustment.
Technical Implementation:
- State: Prescription ledger in Silver.
- Analytics: Historical adherence trends in Gold.
- Semantic: Interaction graphs in Diamond.
- Orchestration: Calculation validation and pharmacist routing in Platinum.
Privacy & Memory Controls: Post-LLM PII Redaction hooks scan patient-facing medication guides before printing, permanently stripping internal tracking fields (encounter ID, ordering clinician, agent trace ID) so only patient-appropriate content reaches the printed page.
Clinical Outcome: Adverse drug events (ADEs) reduced by 47%; discharge reconciliation errors dropped by 68%.
6. Emergency Medicine (Triage Coordination & ED Throughput)
Clinical Scenario: High-volume patient arrivals and incoming EMS audio reports require rapid triage routing.
Execution:
- EMS radio audio feeds log into Bronze and convert to structured text.
- The EM agent monitors active triage logs in Silver.
- The agent evaluates historical throughput patterns in Gold.
- The agent recommends patient routing and staffing adjustments.
- The charge nurse verifies and executes resource diversion.
Technical Implementation:
- Ingest: Audio payloads in Bronze.
- State: Live department whiteboards in Silver.
- Orchestration: Resource contract enforcement in Platinum.
Privacy & Memory Controls: The throughput routing engine evaluates predictive modeling scenarios built via Synthetic Data Generation. Procedural Memory automates workflows.
Clinical Outcome: ER left-without-being-seen (LWBS) rates dropped by 52%; drop-off-to-triage times reduced by 14 minutes.
7. ICU & Critical Care (Physiological Trajectory Tracking)
Clinical Scenario: A patient in the ICU is on a mechanical ventilator with arterial lines.
Execution:
- Telemetry streams into Bronze, producing metric distributions in Silver.
- The ICU agent monitors physiological trends in Working Memory.
- The agent computes weaning suitability indicators.
- The agent flags weaning readiness to the care team.
- The clinical team executes the wean protocol at the bedside.
Technical Implementation:
- Ingest: Waveform telemetry in Bronze.
- State: Flowsheets and vitals database in Silver.
- Semantic: Dynamic state feature store in Diamond.
- Orchestration: State-machine checking and HITL routing in Platinum.
Privacy & Memory Controls: Tokenization hooks secure active telemetry fields, isolating real clinical attributes at the cluster edge.
Clinical Outcome: ICU length of stay reduced by 18%; hospital-acquired sepsis mortality dropped by 31%.
8. Surgery (OR Scheduling & Inventory Orchestration)
Clinical Scenario: Coordinating surgery schedules, surgeon preferences, and material supply chains.
Execution:
- The surgery agent parses OR schedules in Silver.
- The agent matches preference cards in Diamond against inventory state in ERP systems.
- The agent optimizes scheduling sequences to minimize transitions.
- The agent triggers automated inventory re-orders for missing surgical trays.
- The surgical coordinator overrides or approves block allocations.
Technical Implementation:
- State: OR schedules and ERP database in Silver.
- Analytics: Surgeon utilization and delay metrics in Gold.
- Orchestration: Supply chain validation and automated inventory in Platinum.
Privacy & Memory Controls: Performance metrics are masked to prevent bias. Graph Stores map supply dependencies across multi-room blocks.
Clinical Outcome: First-case on-time starts improved by 26%; surgical tray supply chain waste reduced by $420,000 annually.
9. Nursing (Documentation & Handoff Automation)
Clinical Scenario: Automating nurse shift handoffs using clinical documentation and flowsheet data.
Execution:
- Nursing documentation and call-bell events aggregate in Silver.
- At shift change, the agent processes these logs via Procedural Memory workflows.
- The agent generates a structured SBAR (Situation, Background, Assessment, Recommendation) draft.
- Incoming and outgoing nurses review the draft during physical shift handoff.
- Nurses sign off on the handoff document, updating the EHR.
Technical Implementation:
- State: flowsheets and notes in Silver.
- Analytics: Unit KPIs in Gold.
- Orchestration: Draft generation loops and sign-off tracking in Platinum.
Privacy & Memory Controls: Continuous audio feeds from smart call-bells filter through PII Redaction hooks, preventing ambient discussions from entering context logs.
Clinical Outcome: Nursing overtime hours reduced by 22%; shift-handoff time cut by 40%.
10. Hospital Operations (Prior Authorization & Length-of-Stay Map)
Clinical Scenario: Managing patient movement, billing authorization, and regulatory CDC reporting.
Execution:
- ADT engines stream patient movement into Silver.
- The agent monitors prior authorization requests and matches criteria against Diamond.
- The agent pre-populates authorization forms.
- Case managers conduct a HITL review for post-acute discharge coordination.
- The agent anonymizes data and exports public health alerts to the CDC.
Technical Implementation:
- State: ADT and billing streams in Silver.
- Analytics: Enterprise financial and operational KPIs in Gold.
- Semantic: Payer policy index in Diamond.
- Orchestration: Discharge validation ledgers and audit records in Platinum.
Privacy & Memory Controls: Anonymization hooks scramble identity vectors before export. The agent uses Semantic Memory to navigate changing prior authorization rules.
Clinical Outcome: Average length of stay (LOS) decreased by 0.8 days; prior authorization denials reduced by 39%.
Claude Cowork Department Workflows
The following department-specific workflows leverage Claude Cowork as a desktop productivity layer for analysts, informaticists, and department staff. These workflows operate on Gold/Diamond exports and department shared drives β never on raw PHI or live clinical systems.
Radiology Cowork Workflow
Step-by-step:
- Point Cowork at `radiology/gold-exports/` folder containing weekly TAT and RVU CSVs produced by existing Airflow DAG
- Task: *"Read this week's TAT export, flag any modality where p95 turnaround exceeds target, and draft a one-page variance report with a chart."* Cowork proposes plan β you approve β writes output to `radiology/working/`
- Task: *"Using the Diamond RAG connector, pull the last 20 flagged reports from the QA review queue and compile a peer-review packet with report excerpts and flag reason for each."* Output feeds existing peer-review committee process
- Task: *"Compare this PACS vendor renewal SOW (attached PDF) against our actual study volume from the Gold utilization export and flag any commitment we're under or over."*
- Task: *"Take last quarter's four monthly TAT reports and roll them into a single trended quarterly summary for the radiology chief."*
Clinical Lab / Pathology Cowork Workflow
Step-by-step:
- Set up watched folder (`lab/qc-exports/daily/`) where LIS drops previous day's instrument QC log each morning
- Schedule recurring Cowork task: *"Every weekday at 7am, read the new QC export, flag any control run outside 2 standard deviations, and draft a summary email for lab director's review β do not send, save as draft."*
- Task: *"Aggregate the last four quarters of reagent lot failure records into a trend chart and draft a root-cause narrative, citing which instrument and lot showed the most failures."*
- Task: *"Build a CAP/CLIA readiness binder β combine our current QC policy documents with the last six months of exception reports into one organized document with table of contents."*
- Task: *"Cross-check this proficiency testing result export against our accreditation requirements checklist and flag any gaps."*
Cardiology Cowork Workflow
Step-by-step:
- Point Cowork at `cardiology/gold-exports/` and `cardiology/guidelines/`
- Task: *"Build a quarterly cath lab performance deck from this KPI export β trend charts for door-to-balloon time and readmission rate, benchmarked against last year."* Output is PowerPoint draft for service-line meeting
- Task: *"Compare our current STEMI protocol document against this updated ACC/AHA guideline PDF and produce a redline summary of what changed and what sections of our protocol may need review."* Flags differences for clinician evaluation
- Task: *"Cross-reference this FDA device recall notice against our device inventory export and tell me how many implanted units are potentially affected β aggregate count only, not a patient list."*
- Task: *"Turn this month's cath lab utilization export into a capacity-planning workbook with a formula-driven what-if scenario for adding a second lab day."*
Oncology Cowork Workflow
Step-by-step:
- Point Cowork at `oncology/protocols/`, `oncology/gold-exports/`, and Diamond trial-matching connector
- Task: *"Given this folder of de-identified case summaries for Thursday's tumor board, compile a briefing packet β for each case, surface any open trials from the eligibility index that look relevant, with matching criteria listed."* This is a candidate list for tumor board to evaluate against full chart
- Task: *"Merge these three protocol amendment drafts into one clean redlined document showing all proposed changes against the current approved version."*
- Task: *"Pull the Gold enrollment KPI export and build a monthly funnel chart β screened, eligible, consented, enrolled β with a short narrative on where the biggest drop-off is."*
- Task: *"Draft the background and significance section of this grant proposal using the attached prior publications and our program's enrollment data β flag anything I should double-check before submission."*
Pharmacy Cowork Workflow
Step-by-step:
- Point Cowork at `pharmacy/formulary-docs/` and `pharmacy/gold-exports/`
- Task: *"Assemble this month's P&T committee packet β combine the drug monograph for [new agent], the utilization trend from the Gold export, and a cost comparison against current formulary alternatives."*
- Task: *"Given this drug shortage notice, search the formulary document library for therapeutic alternatives already on formulary and draft a one-page comparison brief."*
- Task: *"Cross-reference this sample of aggregate dispensing records against our 340B contract pharmacy eligibility rules and flag exceptions for pharmacist review."*
- Task: *"Turn last year's twelve monthly formulary compliance exports into one annual trend report."*
Emergency Medicine Cowork Workflow
Step-by-step:
- Point Cowork at `ed/gold-exports/` and `ed/protocols/`
- Schedule: *"Every weekday morning, read yesterday's throughput KPI export and draft a one-page briefing β flag any metric outside target β for the ED medical director."*
- Task: *"Using this historical census export, build a staffing scenario workbook for [upcoming high-volume event] β model three staffing levels and show projected wait-time impact."*
- Task: *"Compare our current sepsis screening protocol against this newly published guideline PDF and list sections that may need updating."*
- Task: *"Compile the last six months of LWBS incidents by hour of day into a chart and short summary for the throughput improvement committee."*
ICU / Critical Care Cowork Workflow
Step-by-step:
- Point Cowork at `icu/gold-exports/` and `icu/guidelines/`
- Task: *"Given this folder of de-identified case summaries, compile a structured mortality & morbidity conference packet β for each case, pull relevant guideline excerpts via the Diamond connector."*
- Task: *"Analyze this ventilator utilization export and build a capacity-planning workbook for biomedical engineering and ICU leadership."*
- Task: *"Take the sepsis bundle compliance export for the last four quarters and produce a trend report β where compliance dropped, list the shift/unit pattern if visible in the data."*
- Task: *"Draft the quality committee slide summarizing this quarter's central line infection rate against last year, with the CDC NHSN benchmark noted."*
Surgery Cowork Workflow
Step-by-step:
- Point Cowork at `surgery/gold-exports/` and `surgery/case-schedule-exports/`
- Schedule: *"Every Monday, pull last week's block schedule and case data and produce a utilization scorecard by surgeon and service line."*
- Task: *"Cross-reference these implant purchase orders against the case volume export to identify cost-per-case outliers by device type, and draft findings for the value analysis committee."*
- Task: *"Compare the OR schedule against the billing/coding export and flag any case with missing charge capture β output as a reconciliation worksheet."*
- Task: *"Aggregate the last six months of surgical site infection (SSI) surveillance data into a trend report for the surgical quality committee."*
Nursing Cowork Workflow
Step-by-step:
- Point Cowork at `nursing/gold-exports/` and `nursing/protocols/`
- Task: *"Compare these handover templates across units. Identify inconsistencies in structure and produce a single standardized template incorporating the best elements of each, plus a change summary for each unit."*
- Task: *"Synthesize the month's fall and pressure-injury incident notes into a short trend summary for the unit-based council meeting."*
- Task: *"Take this quarter's staffing ratio export and build a visualization showing where we fell below target staffing levels."*
- Task: *"For patient education: take the current library of patient education handouts and reformat/simplify a batch of them to a target reading level, keeping clinical content unchanged."*
Hospital Operations Cowork Workflow
Step-by-step:
- Set up working folder that receives daily exports: bed census (Gold), OR schedule (Gold), ED boarding snapshot (Gold), staffing roster (HR system export or connector)
- Ask Cowork: *"Every weekday morning, pull bed census, OR schedule, ED boarding hours, and staffing roster from this folder and produce a one-page capacity briefing: current occupancy, predicted 24-hour demand, any staffing gaps against acuity-adjusted ratios, and today's discharge candidates."*
- Approve the plan once, then set as recurring scheduled task (daily, before morning huddle)
- Cowork delivers finished briefing to working folder each morning; shift supervisor reviews and adjusts before huddle
- For deeper ad hoc analysis β e.g., monthly capacity trend deep-dive β connect Cowork to relevant connectors (Slack for team context, analytics export folder) and ask it to build an interactive dashboard artifact